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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf3d9ef833e4eb96ec634b8da21feb68693332d1f231adedf0f554e975240d5' 
  AND token = 'C0Asc0Vu0rIAXZy0LQM3YoUIdxE2EMUnL3R8CfkbthA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}