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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d267b138bd5ceb9b60260a96851fb4ab311fc22579aa9b01438e48bb01e50d' 
  AND token = 'FE2AXvTMrY4GtC/J93we2nVyeMNenm+Zsv6eYX3ud6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}