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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd20d50c9df1ae3bff3d4b15b76fc5a3e9613d60dcbfb6eae232d4fca91e2dff' 
  AND token = '05XbGVmMmvmHR8UWwLlAy3Fb67Fa+a8jtc+7DiZCqaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}