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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506211de66361cb0d9bdab1f3b95b0d54e499c4dd6018bcd553376622784293d' 
  AND token = 'Xj3tbBAltagcN8okPkZGMnaW3NUEdemTnmfJpqRTPRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}