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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddd5c2a9e430c598bf1e48e98ac77a1d360a0dc167852995cd4de9b3040cf906' 
  AND token = 'Kp9hcIuXLH/v++/Dcnt6NUKP3YFrFZVLxb6MCX247+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}