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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b49abc2199bf95b7b1a7b02f5b6af3d3ab009cb5055ee378b3c70bdca6af565' 
  AND token = '0e8MftA3rgxshTgQ0qUgqEgG5HUZdCy4a79z1mVAavE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}