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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1d7e6df06671cfaeeefdcd41bf4bc733d2b15e5cf760015fb34d0975567906' 
  AND token = 'oxAUSV+G9w3HCxCj6Wr8rLryakQcuY39eCn4kX5cUGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}