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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9ea5f3bda86702556c4d025af457250c56ad0119466d9b809716217df69ebb' 
  AND token = '+4ObH2M3xfqVrvx4aUDum8Fw3gCIHRlOWNuygXQgXOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}