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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed1cb375c8b1c8a0eed4bb4f5105db18c71338141106320bec263d07173e3b9' 
  AND token = 'V0b37ldf8kV+Kn1+MztgrkZuYXqiqjesQIR+36TNClE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}