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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7828455b01a4ea72bcdabc32ac27a64a4915479e714a855847731a008b5249e9' 
  AND token = '4Dc3r4c48JHmPcknm+j3qHvITLPxq7wFPHm3z4UTgcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}