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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57e25a7c50b4d546221d19959c52181288fff3030189974dffce070e6d7c7d2' 
  AND token = 'bGspz0r8WCoTg+tKkTwrsEkFcQBIGM1q7mxWQw2j1K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}