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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76803f1135c29406e397367752abfa0c25086c874f97bc44ef5896cb5bacaa3b' 
  AND token = 'd+5nhzoAxtTUm4eYntc+WOgESRdpnNvyftyKoK+bFSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}