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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487269ffdb6baf02984d1bd172afe2c13ae408c141b8b752f9332e46e356d7ca' 
  AND token = 'YWZR45qstJ2+ygauKhHNuQDWi5pk75AIUNsuMCfuXE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}