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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42610fe60c794e8659d90c293e93bfe458994dfcaa7d87aff007d59bc18b322a' 
  AND token = 'GLf+bajD1cN7dovHm/cM7R2BrkPiLpinLVp2xy+4HVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}