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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97c1e7202ddc81615833d4e66c207ae219e99c4112f046076b5d4aae340e3fc' 
  AND token = 'SEk9mmo+Cjwr5Mk/EaeNUeJAvOju3DfO5GdShAIeTaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}