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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcde1c8ac7a27d3ddd081625efb9f52d6e5ef0451f564fc1d405028a61a7d152' 
  AND token = 'VnWZP+eLMHI0d66MARjN6gbloNpIwhHqFgFA6uYGQJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}