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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a877cd61b2f4e77cee03a3ddd7e53ffebdc96a2c3bca3761ad3fdaf86aa5cf4' 
  AND token = '72bb9IinL3XgowW6W0JIFHtOq8IaNvOPdTkZEy2V0u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}