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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4211a0dd840c781870cb7e1110e87641f4310ae87690b1fa258b84c19d8d0fc3' 
  AND token = 'lXt7tTg7HgGsUfQqDXl0njmX2kTPy64aFuvCEeQ9OiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}