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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea5a2ee0507f7a617e65de780c848a656b0e66912b782769fb7d9a77592b7e7' 
  AND token = 'ym+maxAUB91M8UZ/MeiEDnpu4CYbQVWHfMc7StRK3N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}