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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6656414a6509e76beb14f1066b0b5a58c6c10995af52208bd49747b1055cb986' 
  AND token = 'JOI/9KxSOP2fhDZybnQpCDg/L8nT8h0sL2uRsGqyrbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}