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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c753f364a720b3c82191b68fa6c0d32de99abfcd0e8c4ed5792ed3825187aade' 
  AND token = 'ymHpJnYAA/2zusm1pHGcxAU5NpOY+tXX79LKzKO573Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}