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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac78a13120395c177b2a2b3d591100e5342f4ab309e976be4dc623a421411d9' 
  AND token = '/4svcD8k+MrDYPbQ3R3Zh2P70tYCRZF5tvdBh+pJInA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}