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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1bd0eab23e87221bcf4bb8b97e51e56743bee7a37a7e095e9203199a552bf2' 
  AND token = 'IjmJ7Q0Z0ixjC1KdYSJSYwvtc2igxhUQu0W4H0DfUp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}