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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e8b71eb339ffc090b0c3b74bea793653a8ce4b2e69fe282c4536a62e78e6dc' 
  AND token = 'XW4CFo4FEWeQ6tqmZd1HXWwl3BNnWeLRslKFMDth+mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}