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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a222ac4cbb60ec7cd97dd182714a651feed592df8c4d28fe1198240f3f68598f' 
  AND token = 'yZ34xRo3ZMkg+vQw5dg4cdK/ro/7PCF8P9+IF5NnWYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}