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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05614ef6d3de24814133aa1e09d1d11b93ffff16dc19ee8f92ea41a240395ad7' 
  AND token = 'Z/Ol19uQjP6x4ZwPFhS4OhZQX9ablZGKrqr4kvqAtWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}