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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa3c6d9a24e9c82bbab4d300c95386137b3c64c71d7c1881455f2099bee9a47' 
  AND token = 'r9nF5Pe5sg5ItaB1RHW/lq+DpmyZiWCUjvgw39PNk/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}