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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb15b7e27315996c30be425f786432b0eb1f2f5922550fc163f13395d3ce025a' 
  AND token = '0xRfKuKM2O8bGOebv64wvYPianxzM49eIaISBOTVS/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}