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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daba1d69623814dd74f72dddf68f46917ddfba7a1cd424d529057a6c257f1d73' 
  AND token = 'OOxcmxDMNZKZ4WJ5zO4v9cGXrFyg9S2u36uktv6HoHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}