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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06cfd7cc3f4ce0aa3ed3d7d45edc8179c9194b82d76de37f4396d825c70a4041' 
  AND token = 'J0xlng3ObUgHtt2ygB4+58y1WwV0E/U2gNFs4GtTPjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}