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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62223c8a0d1c2e6814a0656058021bd636fdb7b8d8930490a41b152097e13cab' 
  AND token = 'iqNCSae4MyagQ0IwYH6/VmCLHXe2GZ4Aj4qB/aBbNBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}