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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15466ab2ef98975a60407ca46554af4cc0beafc3e142a91855923db40267fa28' 
  AND token = 'TB48xQ82/SfDBkVBkINXIsZq1FQvycnd5sGBC5T/+14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}