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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7aaaad3c7fed5618080d3ca34753c50c7616e09e8a69da8e9a21a61240948d' 
  AND token = '4NnaiNRkYwsHQCwgjpyCckaT5cFafmPcUEHYPKb4rk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}