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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20fe16654a8ee37ab43a656e6fd37fd068fd6a8e3acced94302d435f59b5227f' 
  AND token = 'aGCI6To8iJOEhbfUfOskaTyeiZCvgg+7wdUEcbX2x28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}