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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04dd64dcfe7e95d8dc08167ffe242921feeb8d3f173b290b3d143154c0c6e376' 
  AND token = 'RCoWr+ifNlDssn+Oq7I76+QNUFHiRC194rdDB093ZtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}