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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045208b077ff2ad215f557d59a519a3cf0b5eaf6caf71a77d7dd31cdc4829733' 
  AND token = 'akLRmqYxTSz3ixkWcQWU9lPMXZbVA8QXFiJ+x32KoFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}