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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defbe0239cb02c479e63741eecaeea90241c02ad198354eeb2f7d70130a17fa8' 
  AND token = 'rLIl42QWKvCbkNQ7T76nAK6UUG9dj7hge1YlDxaB8+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}