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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2ea21dbdc84f68a1966fed7f1a8be590fb0ccca030c69aa76c6e54c908bead' 
  AND token = 'uF1GsToRrzAXQqvCziTSyrLp3M8Z2gGoub2jx1xcpJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}