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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd567e16eb225d67e071a37c73cbeca52d967f80a15f710c9fe1e3b1bc5cd413' 
  AND token = 'Y4uk+2CUtK+vtsG+IrmK/hWF8UxH2PcEmaeQrP3r6VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}