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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbee9046c38315309e560a4188725d12a94ee132fd9f837b25472f440015e3d0' 
  AND token = '4K0GFbLiymvx/r6AXUhAIiJsvmPHV71TuAVhsENWIW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}