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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1559834f12d500316e3015b0dee70b04d6d5faa634263243f103f76d3a1857d' 
  AND token = 'SmFLC7iOJbSDxRZC3r71hI2UA9bpzeGJcgGX0Vs8+Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}