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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150cc91af84dce5406a89d94b21d0278900d005d092239b386b7aca202fcb94d' 
  AND token = 'ABaZ7L6RMpR/S9bu3xUjYXS3TLo08oii3IzOEOZ1UgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}