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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f91c1d76cf9fa5247722d95e95de4bcfb0f28d122cc3415ad023d41f4e00b4cb' 
  AND token = 'v4RyoqrlY3NpwfbENw8IN7cPurrDLsemxRzpzyI+eFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}