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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05ea567f34611e833a9884ba410ea19ce1a36c245069e97838a1c90c88704de' 
  AND token = 'KUfhIxJjlwjKaoERThcrzCg5A12lqF9zMb2QKC/ORIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}