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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5ee9476e3f246a86ef4d806f6bf1683ab349e45d5224cc13eecdd72690b028f' 
  AND token = 'LqwGYqorkUUUMYypCip8b1Wu8pyiLvcySAeT5jGWKwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}