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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e1214a9850cc7be17bdbc654367cc3082cf79c468b0e76eba4492e8eacc904' 
  AND token = 'BbFIKDUauVbD7Uag2H2U17OQXY7sCdWMDTgyACIv/Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}