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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16edc04991b025c327119519dd5b66b5cf91296a3b869ed578e222a2839ed12' 
  AND token = '3qwOeA2SQbVy/NUiXnUoJeReysi9K1ETA6t5YY/Ykp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}