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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b16f33e374cb64ff80b1add28692b1af74a3e837f47b07aae488c1780735b3' 
  AND token = 'K5gID8LOeF7CFjkYoQOGEGVvTJUJ5D7BC1eFO1iw6PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}