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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b2dfa3103eeb7fd8f0440daedd87fdc44f83128c21c0966fcde9d1012845449' 
  AND token = 'bDsBeiLxggn6A3RjmVwK2kxyyNR3ELHDxkWzSvMrqOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}