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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135f540e43ef41333e3ee13a56435f8e7f1d4f94e3e463beb839c64015d6eacf' 
  AND token = 'yW/UyzisRztjQg5L+b7yfvZGrabidjZdEQQ30BcvW8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}